The Tsurpu Gyeltsab is an important Karma Kamtsang incarnation line established in the fifteenth century with a seat at Tsurpu Monastery. The First Tsurpu Gyeltsab, Peljor Dondrub, was identified by the Sixth Karmapa, Tongwa Donden as the reincarnation of Kharchen Pelgyi Wangchuk, one of the twenty-five disciples of Padmasambhava. The Sixth Karmapa appointed him the regent, or gyeltsab of his own seat at Tsurpu.