Wensapa Lobzang Dondrub (dben sa pa blo bzang don grub) was born in Lhaku (lha khud) in Tsang, in a place called Wensa (dben sa) in 1505. His father was Sonam Dorje (bsod nams rdo rje) and his mother was Pel Dzomkyi (dpal 'dzom skyid). His childhood name was Gompo Kyab (mgon po skyabs).
At a very young age Wensapa met his first teacher, Je Kyabchok Pelzang (rje skyabs mchog dpal bzang), the abbot of Wensa Monastery (dben sa dgon). He is said to have been an extraordinary student and practitioner even from youth, quickly surpassing the knowledge and understanding of all of his peers. As well, Wensapa is said to have had great, spontaneous, and natural faith for Tsongkhapa Lobzang Drakpa (tsong kha pa blo bzang grags pa, 1357-1419), and prayed to be able to embody the essence of his teachings. In pursuit of this goal, at the age of eleven, he took ordination as a novice monk at a monastery named Chokhor Uding (chos 'khor dbus sdings). Drakpa Dondrub (grags pa don grub) of Lharitse (lha ri rtse) served as abbot and Tsultrim Rinchenpa (tshul khrims rin chen pa) was preceptor. He was given the name Lobzang Dondrub.
Soon after Lobzang Dondrub traveled to Drepung Monastery ('bras spungs) where he studied Lamrim (lam rim) and philosophical texts, and received instruction on the practices of highest yoga tantras with a number of lamas, particularly from Lharipa Drakpa Dondrub. When he was seventeen, ill with smallpox during an epidemic in Lhasa, he became the disciple of the siddha Chokyi Dorje (chos kyi rdo rje, b.c.1457), and from him received the detailed instructions on the oral tradition of Tsongkhapa, taking his place as a lineage holder of the Ganden Oral Tradition. Chokyi Dorje transmitted the oral tradition of Tsongkhapa's lineage of Ganden Mahāmudrā (dga' ldan phyag chen), which Tsongkhapa is said to have received from Mañjuśrī himself, together with the root text of the transmission, the Trulpai Lekbam Chenmo (sprul pa'i glegs bam chen mo). From Chokyi Je Lodro Gyeltsen (chos kyi rje blo gros rgyal mtshan) he received the instructions, transmission, and permissions for the Nartang Gyatsa (snar thang brgya rtsa), the meditation instructions of Atiśa, Guhyasamāja, among other tantric teachings.
Chokyi Dorje invited him to join him at his hermitage, Garmo Cho Dzong (mgar mo chos rdzong) in Tashi Dzong (bkra shis rdzong), to the West of Shigatse. Wensapa went to there when he had recovered from his smallpox, and there Cho Dorje gave him the full transmission of the Lamrim and the Ganden Oral tradition. From there Wensapa next went to a meditation cave known as Pema Chan (pad+ma can), a place also referred to as Pema O (pad+ma 'od) where he practiced these and other doctrines Chokyi Dorje had transmitted to him. There he lived as an Indian-style siddha, smearing his body with ash and sitting in seven-pointed posture for days on end. There has been some speculation that he also engaged in sexual yoga with a consort at this time. He also, at the age of twenty, practiced Guhyasamāja in the hermitage of Gyelwa Gyung (rgyal ba rgyung) in Drakgyawo ('brag rgya bo).
Wensapa gave his first teachings at the hermitage of Pema O, and from then on taught extensively throughout the land, residing at various Geluk institutions in Tsang and U, includind Drepung, where at the age of thirty-three he took complete ordination vows from Gendun Gyatso (dge 'dun rgya mtsho, 1476-1542), who would posthumously be known as the Second Dalai Lama. At Tashilhunpo (bkra shis lhun po) in Shigatse he met Lekpa Dondrub (legs pa don grub), with whom he collaborated on in several of his compositions. At Sera Monastery (se ra dgon) he received additional teachings and empowerments from Gendun Gyatso. Back in Tsang, he received teachings from Paṇchen Jangchub Lodro (paN chen byang chub blo gros), Ngari Lochen Namgyel (mnga' ri lo chen rnam rgyal) and Lekpai Lodro (legs pa'i blo gros).
Wensapa's most important disciple was Sanggye Yeshe, who became his primary lineage holder.
In 1566 Wensapa passed away. During the cremation of his body many miraculous signs are said to have appeared, including rainbows and flowers that fell from the sky. His remains were interred at Wensa monastery. Around 1641, his recognized reincarnation, Lobzang Chokyi Gyeltsen (blo bzang chos kyi rgyal mtshan, 1570-1662) was given the title of Paṇchen Lama by the Fifth Dalai Lama, Ngawang Lobzang Gyatso (ta la'i bla ma 05 ngag dbang blo bzang rgya mtsho, 1617-1682); Wensapa was thus posthumously given the title of Third Paṇchen Lama.
Images

Avalokiteśvara Sāhasrabhujalokeśvara
Avalokiteśvara with one thousand hands and eleven faces in the nyungne tradition of Gelongma Pelmo with Geluk lineage teachers of Tashilhunpo Monastery.
Rubin Museum of Art, acc.# F1997.1.6
དཔྱད་གཞིའི་ཡིག་ཆ་ཁག།
Willis, Janice D. 1995. Enlightened Beings: Life Stories from the Ganden Oral Tradition. Boston: Wisdom Publications.
Willis, Janice D. 1985. “Preliminary Remarks on the Nature of rNam-thar: Early dGe-lugs-pa Siddha Biographies.” In Soundings in Tibetan Civilizations. Barbara Aziz and Matthew Kapstein, eds. Delhi: Manohar.
Tshe mchog gling Yongs 'dzin Ye shes rgyal mtshan. 1970. Biographies of Eminent Gurus in the Transmission Lineages of the teachings of the Graduated Path, being the text of: Byang chub Lam gyi Rim pa'i Bla ma Brgyud pa'i Rnam par Thar pa Rgyal mtshan Mdzes pa'i Rgyan Mchog Phul byung Nor bu'i Phreng ba (1787). New Delhi: Ngawang Gelek Demo, vol 2, pp. 2-57.
Yongs 'dzin ye shes rgyal mtshan. 1990. Lam rim bla ma brgyud pa'i rnam thar. Lhasa: Bod ljongs mi dmangs dpe skrun khang.